NCT07447635NARecruitingAccepts Healthy Volunteers

Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

H. Lee Moffitt Cancer Center and Research Institute

Start Date

5/15/2026

Completion Date

12/1/2029

Summary

This study will examine the efficacy of Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) compared to standard care among cancer survivors who smoke cigarettes and engage in at-risk alcohol use. Investigators will evaluate implementation outcomes through structured stakeholder interviews across medical centers, cancer-focused organizations, and community-based programs in Florida, and will conduct a cost-assessment and an incremental cost-effectiveness analysis of the two conditions.

Detailed Description

The primary aim of this study is to test the efficacy of MBRP-SA compared with standard care among cancer survivors, explore potential moderators, mechanisms, and predictors of treatment effects, and evaluate implementation outcomes to guide future adoption of MBRP-SA.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * ≥18 years old * History of a cancer diagnosis at any point in lifetime * Smoked ≥1 cigarette/day in past month * At least one binge drinking episode in past month or exceeds weekly drinking limits * Motivated to quit smoking and modify alcohol use in next 30 days * Valid home address in Florida * English-speaking, reading, and writing ability Exclusion Criteria: * Pregnancy or lactation * Active psychotic disorder * History of severe alcohol withdrawal * Current use of tobacco cessation medication or other treatments to quit smoking * End-of-life or hospice care * Household member already enrolled

Interventions

BEHAVIORAL

Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA)

BEHAVIORAL

Quitline Support

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Conditions

Smoking CessationAlcohol Use

Locations

Moffitt Cancer Center

Tampa, Florida 33612

United States