Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
Start Date
6/12/2026
Completion Date
3/1/2030
Summary
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an individuals own voice and the movements of their speech muscles, and a motor system that builds and reads out learned motor patterns. The investigators are studying how these systems work together and how they differ across individuals. Investigators will test 90 adults between 18 and 50 years old, including people who stutter, people with dyslexia, and people with typical speech and reading development. Participants will complete several short speech tasks in which the sounds they hear or the movements of their jaw or larynx are briefly changed. These responses will be used to measure each person's speech motor skills and to estimate the settings of a computer model called "SimpleDIVA," which simulates how the brain controls speech. Participants will also complete an MRI scan so investigators can measure the structure and connectivity of different brain regions. These measures will help investigators understand how individual differences in the brain relate to the speech motor control skills we observe. Participants will also complete sessions with noninvasive brain stimulation (transcranial current stimulation, or tCS) to examine how stimulation of specific areas of the brain affects responses during the speech tasks. The knowledge gained from this study will help researchers understand why speech motor skills vary across people and how differences in neural function may contribute to conditions such as stuttering and dyslexia.
Eligibility Criteria
Age Range: 18 years to 50 years
Interventions
Unpredictable auditory feedback perturbation: 2 behavioral sessions
Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions
Sustained F1 auditory feedback perturbation
Sustained F0 auditory feedback perturbation
Reflexive somatosensory perturbation
Anodal tCS targeting pSTG and vSSC
Anodal tCS targeting left or right vPMC
Sham tCS targeting pSTG or vSSC
Sham tCS targeting left vPMC or right vPMC
Conditions
Locations
Boston University Charles River Campus
Boston, Massachusetts 02115
United States
Boston University
Boston, Massachusetts 02215
United States