NCT07464093NARecruiting
STABLE Pilates for Hypermobility
Brigham and Women's Hospital
Start Date
7/1/2026
Completion Date
12/1/2027
Summary
This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.
Detailed Description
In this study, investigators are looking at whether 6 weeks of Pilates-based exercise led by a licensed physical therapist can help with hypermobility-related symptoms, like pain. Pilates is a gentle mind-body exercise with an emphasis on muscular control, postural awareness, and breathing that may be particularly well-suited for managing hypermobility. Exercises are mostly floor-based and focus on developing muscular strength and stability which may improve pain and symptom management.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* ≥ 18 years old;
* Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD;
* Self-reported persistent pain ≥ 3 months;
* A minimum of 3/10 self-reported pain intensity in the past week
* Able to get on and off the floor without assistance;
* Able to communicate fluently in English; and
* Able to provide written, informed consent
Exclusion Criteria:
* Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months;
* Recent surgery or acute bone, joint or nerve injury (\<6 months);
* Have a history of a severe or progressive neurological or movement disorder;
* Pregnant, planning to become pregnant during the study, or currently breast feeding;
* Unable to get on and off the floor without assistance;
* Unable to complete study procedures due to cognitive impairment;
* Unable to provide written, informed consent; or
* Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.
Interventions
BEHAVIORAL
Pilates
BEHAVIORAL
Education
Conditions
Ehlers-Danlos Syndrome (EDS)Hypermobile EDS (hEDS)Hypermobile Spectrum Disorder
Locations
Brigham and Women's Hospital
Chestnut Hill, Massachusetts 01467
United States