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NCT07464093NARecruiting

STABLE Pilates for Hypermobility

Brigham and Women's Hospital

Start Date

7/1/2026

Completion Date

12/1/2027

Summary

This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.

Detailed Description

In this study, investigators are looking at whether 6 weeks of Pilates-based exercise led by a licensed physical therapist can help with hypermobility-related symptoms, like pain. Pilates is a gentle mind-body exercise with an emphasis on muscular control, postural awareness, and breathing that may be particularly well-suited for managing hypermobility. Exercises are mostly floor-based and focus on developing muscular strength and stability which may improve pain and symptom management.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * ≥ 18 years old; * Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD; * Self-reported persistent pain ≥ 3 months; * A minimum of 3/10 self-reported pain intensity in the past week * Able to get on and off the floor without assistance; * Able to communicate fluently in English; and * Able to provide written, informed consent Exclusion Criteria: * Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months; * Recent surgery or acute bone, joint or nerve injury (\<6 months); * Have a history of a severe or progressive neurological or movement disorder; * Pregnant, planning to become pregnant during the study, or currently breast feeding; * Unable to get on and off the floor without assistance; * Unable to complete study procedures due to cognitive impairment; * Unable to provide written, informed consent; or * Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.

Interventions

BEHAVIORAL

Pilates

BEHAVIORAL

Education

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Conditions

Ehlers-Danlos Syndrome (EDS)Hypermobile EDS (hEDS)Hypermobile Spectrum Disorder

Locations

Brigham and Women's Hospital

Chestnut Hill, Massachusetts 01467

United States