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NCT07476937NARecruiting

Differences in Rest, Emotion, and Arousal Modulation in Youth

University of Pittsburgh

Start Date

7/20/2026

Completion Date

8/1/2030

Summary

The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10). In a subset of children with elevated sensory responsivity, a sensory-based bedtime manipulation targeting bedtime arousal levels will be tested.

Detailed Description

This study is a cross-sectional study with a pilot pre-post intervention trial with a subset of participants. A total of 60 autistic children and caregivers will be recruited to complete questionnaires, one lab visit during which sensory responsivity to standardized sensory stimuli will be measured, and two weeks home-based data collection using daily diaries and actigraphy devices (both caregiver and child). In a subset of 30 participants with elevated sensory over-responsivity and bedtime resistance, participants will be invited to complete the second part of the study- a open pilot study. These participants will complete a baseline interview and a lab-based training session to learn the caregiver-mediated Power Down protocol. The Power Down protocol is a standardized gentle pressure massage with a mindfulness script that aims to decrease autonomic arousal through proprioception and tactile input. Caregivers will complete the Power Down and a home-based data collection protocol for 2 weeks. During this time, caregivers and child will also wear actigraphy devices and complete daily diaries. Upon completion of the study, participants will complete exit questionnaires and an exit interview.

Eligibility Criteria

Age Range: 6 years to 10 years

Inclusion Criteria: 1. Youth between the ages of 6 and 10 years old 2. Caregiver-reported autism diagnosis and \>11 on Social Communication Questionnaire 3. Caregiver-reported bedtime resistance (\>12 on Children's Sleep Habits Questionnaire-Autism; Sleep Initiation subscale - 3-point scale, 6 questions) 4. Caregiver willing to participate in all bedtimes during study 5. Stable medication use (e.g., no changes within 2 weeks) Exclusion Criteria: 1. Participants will be excluded if they do not understand English or are unable to travel to the lab (Pittsburgh, PA). 2. Concurrent diagnosis of sleep apnea, narcolepsy, or major psychiatric disorder (e.g., major depression, bipolar). 3. Unstable medication use (dose or timing). 4. Current behavioral treatment for sleep disorder

Interventions

BEHAVIORAL

Power Down bedtime manipulation

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Conditions

AutismSleep Disturbances in ChildrenSleep

Locations

University of Pittsburgh

Pittsburgh, Pennsylvania 15219

United States