NCT07483203Recruiting

A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

Mayo Clinic

Start Date

4/28/2026

Completion Date

5/1/2028

Summary

The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve intervention, and to identify patterns predicting reversibility of TR and RV dysfunction.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * ≥18 years old; AND * Scheduled for valve procedures Exclusion Criteria: * Congenital heart disease (except for bicuspid aortic valve), OR * Carcinoid heart disease, OR * Valvular mass, OR * Endocarditis, OR * Any other condition that, in the opinion of the investigator, would impair their ability to complete the study

Interventions

DIAGNOSTIC_TEST

Echocardiogram

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Conditions

Pulmonary Vascular DiseaseValvular Heart Disease

Locations

Mayo Clinic in Rochester

Rochester, Minnesota 55905

United States