NCT07485738NARecruiting
The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery
Weill Medical College of Cornell University
Start Date
3/30/2026
Completion Date
3/1/2032
Summary
The purpose of this study is to learn more about a tool called Transit-Time Flow Measurement (TTFM). TTFM uses sound waves during surgery to check how well blood is flowing through blood vessels. This helps doctors see if the blood flow is good during coronary artery bypass grafting (CABG), which is a type of heart surgery
Detailed Description
The SMARTFLOW:Patency trial is designed to fill this critical evidence gap by evaluating the impact of CABG graft quality assessment by TTFM on clinical outcomes in a large randomized cohort. SMARTFLOW:Patency will evaluate the impact of CABG graft quality assessment by TTFM on graft patency.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
1. Age \>18 years
2. First-time, non-emergent isolated multivessel CABG through median sternotomy
3. Willing and able to provide written informed consent and comply with all study procedures, including QOL questionnaires
Exclusion Criteria:
1. Reoperation
2. Emergency procedures
3. Combined CABG + other cardiac or non-cardiac surgery
4. Isolated single vessel CABG
5. Minimally invasive CABG
6. Inability to undergo coronary computed tomographic angiography (CCTA)
7. Unable to provide written informed consent or comply with all the study procedures.
Interventions
DEVICE
Transit-Time Flow Measurement (TTFM)
Conditions
CABG Graft IntegrityCABGBlood FlowTransit-time Flow MeasurementHeart Disease
Locations
Weill Cornell Medicine/NewYork Presbyterian Hospital
New York, New York 10022
United States