Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement
Start Date
6/29/2026
Completion Date
4/30/2027
Summary
The purpose of this study is to improve pain management for participantswho need osmotic dilators for cervical preparation the day before their second trimester abortion procedure.
Detailed Description
The purpose of this study is to improve pain management for participantswho need osmotic dilators for cervical preparation the day before their second trimester abortion procedure. Osmotic dilators are sticks that are inserted into the cervix. They soak up fluid and expand overnight, gently opening the cervix. We are studying an injection of ketorolac (a liquid anti-inflammatory medication similar to ibuprofen) combined with lidocaine (a liquid numbing medication), which is injected vaginally to the area surrounding the cervix. Ketorolac is approved by the U.S. Food and Drug Administration (FDA) for intravenous (IV) and intramuscular injection and has been studied as a paracervical injection for participants having first trimester abortion procedures in the office. It has not previously been studied for osmotic dilator insertion.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Ketorolac
oral ibuprofen
Placebo
Lidocaine HCl 1%
Saline
Conditions
Locations
Rush University Medical Center
Chicago, Illinois 60612
United States