NCT07489417NARecruitingAccepts Healthy Volunteers
Impact of Sleep Restriction on Blood Pressure Reactivity
University of Missouri-Columbia
Start Date
3/4/2026
Completion Date
8/1/2027
Summary
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
Eligibility Criteria
Age Range: 18 years to 45 years
Inclusion Criteria:
* Healthy adult men and women
* 18-45 years of age
* BMI \< 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
* Non-pregnant, non-breastfeeding, and non-nicotine users
* Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
* Premenopausal
Exclusion Criteria:
* No acute or chronic conditions
* Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
* Self-reported history of irregular sleep
* Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension
Interventions
BEHAVIORAL
Sleep Restriction
Conditions
SleepBlood Pressure
Locations
University of Missouri
Columbia, Missouri 65211
United States