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NCT07489885PHASE2Recruiting

A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis

InventisBio Co., Ltd

Start Date

6/3/2026

Completion Date

12/1/2027

Summary

A Study looking at the safety and efficacy of D-2570 in Participants with Plaque Psoriasis

Detailed Description

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Study to Evaluate the Efficacy and Safety of D-2570 in Participants with Moderate to Severe Plaque Psoriasis

Eligibility Criteria

Age Range: 18 years to 70 years

Inclusion Criteria: * Participants with a diagnosis of plaque psoriasis with no significant flares of disease activity for at least 6 months before signing the informed consent * Participants have moderate to severe plaque psoriasis as defined by a total body surface area (BSA) ≥10%, a Psoriasis Area and Severity Index (PASI) score ≥ 12 and a Physician's Global Assessment (PGA) score ≥ 3. * Within normal ranges of laboratory assessments Exclusion Criteria: * Any comorbidities or past medical conditions as outlined in the protocol that would interfere with study assessments as deemed by the Investigator

Interventions

DRUG

D-2570 Tablet

DRUG

Placebo Tablets

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Conditions

Psoriasis

Locations

Study Center

Birmingham, Alabama 35244

United States

Study Center

Phoenix, Arizona 85008

United States

Study Center

Chula Vista, California 91910

United States

Study Center

Fountain Valley, California 92708

United States

Study Center

Fremont, California 94538

United States

Study Center

Los Angeles, California 90017

United States

Study Center

Los Angeles, California 90024

United States

Study Center

San Diego, California 92123

United States

Study Center

Fort Lauderdale, Florida 33308

United States

Study Center

Miramar, Florida 33027

United States

Study Center

Ocala, Florida 34470

United States

Study Center

Tampa, Florida 33607

United States

Study Center

Sandy Springs, Georgia 30328

United States

Study Center

Savannah, Georgia 31419

United States

Study Center

Idaho Falls, Idaho 83404

United States

Study Center

Clarksville, Indiana 40241

United States

Study Center

Louisville, Kentucky 40241

United States

Study Center

Mayfield Heights, Ohio 44124

United States

Study Center

Philadelphia, Pennsylvania 19103

United States

Study Center

San Antonio, Texas 78218

United States