Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)
Start Date
7/1/2026
Completion Date
9/1/2028
Summary
To characterize the impact of orthostatic hypotension (OH) and Vasovagal syncope on signals measured using a wearable Holter monitor in the clinic and ambulatory setting. To evaluate the relationship of signals measured from the Holter monitor with reported symptom severity of orthostatic intolerance per standard data collection, analysis, and questionnaires.
Detailed Description
This is a non-randomized feasibility study that will enroll up to 40 participants that have undergone a previous autonomic reflex screen (ARS) assessment and were either diagnosed with OH or reflex syncope or considered to be control subjects for this study. A minimum of 20 subjects diagnosed with reflex syncope; a maximum of 15 subjects diagnosed with OH syncope and a maximum of 15 control subjects will be enrolled. There will be one in person study visit and a 21 day follow up period per subject.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Wearable holter monitor
Wearable holter monitor
Conditions
Locations
Mayo Clinic Foundation
Rochester, Minnesota 55905
United States