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NCT07548632PHASE2, PHASE3Recruiting

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

Oculis

Start Date

4/16/2026

Completion Date

12/1/2026

Summary

The primary objective of this study is to evaluate the efficacy and safety of the topical ophthalmic administration of licaminlimab as compared to vehicle in participants with Dry Eye Disease and a specific genotype.

Eligibility Criteria

Age Range: 18 years to No maximum

Key Inclusion Criteria: * Physician diagnosis of Dry Eye Disease in the past 6 months * Use of over-the-counter tears * Must agree to genotype testing Key Exclusion Criteria: \- Have a history or presence of any disorder or condition that may, in the opinion of the Investigator, likely interfere with the interpretation of the study results or participant safety.

Interventions

OTHER

Artificial Tear Run-in

DRUG

licaminlimab

OTHER

Vehicle of licaminlimab

Interested in This Trial?

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Conditions

Dry Eye Disease (DED)

Locations

East West Eye Institute

Aliso Viejo, California 92656

United States

Orange County Ophthalmology

Garden Grove, California 92843

United States

Global Research Management

Glendale, California 91204

United States

LoBue Laser and Eye Medical Center

Murrieta, California 92562

United States

Eye Research Foundation

Newport Beach, California 92664

United States

North Bay Eye Associates, Inc.

Petaluma, California 94954

United States

Vision Institute

Colorado Springs, Colorado 80907

United States

Segal Drug Trials, Inc.

Delray Beach, Florida 33484

United States

Oculus Research, Inc.

Garner, North Carolina 27529

United States

CORE, Inc

Shelby, North Carolina 28150

United States

Scott & Christie and Associates

Cranberry Township, Pennsylvania 16066

United States

Erie Retina Research

Erie, Pennsylvania 16507

United States

Total Eye Care, PA

Memphis, Tennessee 38119

United States

Piedmont Eye Center, Inc.

Lynchburg, Virginia 24502

United States