Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Start Date
5/29/2026
Completion Date
11/19/2027
Summary
The purpose of this clinical study is to look at the safety of the medicine Cagrilintide when compared to placebo in people who do not tolerate marketed glucagon-like peptide-1 (GLP-1) therapies and who live with overweight or obesity. Participants will get either Cagrilintide (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participant will get is decided by chance. The study will last for about 8 months.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Cagrilintide
Placebo (matched to Cagrilintide)
Conditions
Locations
Diablo Clinical Research, Inc.
Walnut Creek, California 94598
United States
Northeast Research Institute
Fleming Island, Florida 32003
United States
Jacksonville Ctr For Clin Res
Jacksonville, Florida 32216
United States
Center for Diab,Obes & Metab
Pembroke Pines, Florida 33024
United States
Encore Medical Research of Weston
Weston, Florida 33331
United States
Monroe Biomedical Research, LLC
Monroe, North Carolina 28112
United States
Accellacare
Wilmington, North Carolina 28401
United States
Coastal Carolina Research Ctr
North Charleston, South Carolina 29405
United States
Holston Medical Group_Bristol
Bristol, Tennessee 37620
United States
Amarillo Medical Specialists
Amarillo, Texas 79124
United States
Elligo Clin Res Centre
Austin, Texas 78704
United States