NCT07635329NARecruiting
Home-based Vision Rehabilitation Guided by Brain Imaging
Georgetown University
Start Date
7/1/2026
Completion Date
3/31/2030
Summary
The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss. Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.
3. Unilateral or bilateral focal brain damage causing visual field loss.
4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
5. Eligible for MRI based on standard safety screening.
Exclusion Criteria:
1. Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation.
2. Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
3. Ocular disease or disorder.
Interventions
BEHAVIORAL
High-level perceptual learning-based training
BEHAVIORAL
Low-level perceptual learning-based training
Conditions
Visual Field DefectStrokeHemianopia HomonymousQuadrantanopiaCortical BlindnessVisual Field Defect, PeripheralVisual Field LossTraumatic Brain InjuryBrain Tumor
Locations
Georgetown University Medical Center
Washington D.C., District of Columbia 20057
United States