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NCT07635784Recruiting

Prospective HemorrhoIdaL EmboliSation (PILES) Registry

Joint & Vascular Institute

Start Date

1/18/2026

Completion Date

1/1/2032

Summary

The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults aged 18 years or older that have not responded to medical therapy. The main question it aims to answer are: 1\) Does HAE lead to sustained improvement in bleeding (HDSS scores over 12-36 months? Participants will: * Undergo HAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to medical therapy, referred for HAE. Exclusion Criteria: * Pregnancy, coagulopathy, severe comorbidities, or inability to consent.

Interventions

PROCEDURE

Hemorrhoid Artery Embolization

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Conditions

HemorrhoidInternal HemorrhoidsHemorrhoid BleedingHemorrhoidal BleedingInternal Hemorrhoid

Locations

Joint and Vascular Institute

Libertyville, Illinois 60048

United States