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NCT07638384NARecruitingAccepts Healthy Volunteers

Evaluation of Muscle Oxygen With MRI

Icahn School of Medicine at Mount Sinai

Start Date

8/1/2026

Completion Date

5/7/2029

Summary

Demonstration of soft tissue hypoxia on MRI using external compression and muscle contraction.

Detailed Description

Participant will undergo a single MRI examination. Standard orthopedic Sarmiento brace/ shell applied to participant's arm. Inside the brace will be a standard blood pressure cuff with a standard brace soft foam attached; blood pressure cuff will be partially inflated. Participant will also be asked to lift MRI compatible 10 lb. weight. Muscle oxygenation will be actively measured using MRI. No medications are being given, and no invasive devices are being used.

Eligibility Criteria

Age Range: 20 years to 64 years

Inclusion Criteria: * Alert and oriented. * Able to lift 10lbs. and hold for 30 seconds * Not claustrophobic. * Intact sensation in right upper extremity. Exclusion Criteria: * Latex allergy or allergy to isopropyl alcohol. * Skin injury or decreased sensation on right upper extremity.

Interventions

PROCEDURE

Compression and Contraction

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Conditions

Muscle Oxygenation

Locations

Mount Sinai Hess Center

New York, New York 10029

United States