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NCT07649057Recruiting

A Study of a Urine Test to Detect Colorectal Cancer

Memorial Sloan Kettering Cancer Center

Start Date

6/11/2026

Completion Date

6/11/2028

Summary

The purpose of this study is to find out whether a urine test can detect colorectal cancer (CRC) and precancerous polyps in participants living in Ghana, Tanzania, and South Africa.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Patient presents with one of the following: * Patients with symptoms of CRC (such as rectal bleeding for a week) -OR- * Patients who present for a screening colonoscopy -OR- * Has received one of the following within 3 weeks of the planned urine collection * Patients with a pathologic diagnosis of CRC either by colonoscopy or resection specimens -OR- * Patients with colonoscopy demonstrating adenomatous polyps -OR- * Patients with colonoscopy demonstrating no colon or premalignant or malignant pathology * Age ≥ 18 * Willingness to participate in the study

Interventions

DIAGNOSTIC_TEST

3-metabolite biosensor

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Conditions

Colorectal CancerPrecancerous PolypRectal BleedingCRC

Locations

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York 10065

United States

Korle Bu Teaching Hospital (Data Collection Only)

Accra,

Ghana

Wits Donald Gordon Medical Centre (Data Collection Only)

Johannesburg,

South Africa

Kilimanjaro Christian Medical Centre (Data Collection Only)

Moshi,

Tanzania