Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
Start Date
7/28/2026
Completion Date
1/21/2028
Summary
This study will test an experimental drug called olatorepatide ("study drug") to determine how safe and effective this drug is compared to placebo and how easily the body can accept this drug at different doses and dosing schedules without causing side effects, as well as how the drug is processed in the body by participants with overweight or obesity but do not have diabetes. The study is looking at: * What side effects the study drug might cause * How much study drug is in the blood at different times * How well the study drug works * What effects the study drug may have on the body at different dosing schedules * If the body makes antibodies to the study drug as this may cause the study drug to not work as well
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Olatorepatide
Placebo
Conditions
Locations
AMR Clinical - Mobile
Mobile, Alabama 36608
United States
Diablo Clinical Research - Flourish Research
Walnut Creek, California 94598
United States
Chase Medical Research
Waterbury, Connecticut 06708
United States
Alliance for Multispecialty Research (AMR) Clinical Miami
Doral, Florida 33172
United States
AMR Clinical - Fort Myers
Fort Myers, Florida 33912
United States
AGA Clinical Trials
Hialeah, Florida 33012
United States
Flourish Research, Nature Coast Clinical Research
Inverness, Florida 34452
United States
Flourish Research, Jacksonville Center for Clinical Research
Jacksonville, Florida 32216
United States
K2 Medical Research Maitland LLC, Main Office
Maitland, Florida 32751
United States
The IMA Group, IMA Clinical Research St. Petersburg
St. Petersburg, Florida 33704
United States
Charter Research LLC - The Villages
The Villages, Florida 32162
United States
Clinical Site Partners, LLC DBA Flourish Research
Winter Park, Florida 32789
United States
Charter Research LLC - Chicago
Chicago, Illinois 60618
United States
Flourish Research - Chicago
Chicago, Illinois 60625
United States
AMR Clinical - Chicago Oak Brook
Oak Brook, Illinois 60523
United States
AMR Clinical - Wichita
Wichita, Kansas 67207
United States
AMR Clinical - Lexington
Lexington, Kentucky 40509
United States
Velocity Clinical Research - Omaha
Omaha, Nebraska 68134
United States
NYC Research Inc
New York, New York 10016
United States
Rochester Clinical Research
Rochester, New York 14609
United States
Tribe Clinical Research
Greenville, South Carolina 29607
United States