Back to Trials
NCT07694206Recruiting

Digital and Plasma Biomarkers in Delirium

Scripps Health

Start Date

5/28/2026

Completion Date

12/31/2027

Summary

The goal of this observational study is to learn if there are potential digital and plasma-based biomarkers that could help detect, predict, and prognosticate delirium in older adult patients who are admitted to the intensive care unit (ICU). The main question DELTA aims to answer is: Can digital biometrics predict and detect delirium in older adult ICU patients? Do biomarkers of neurodegeneration fluctuate in ICU patients in such a way that delrium could potentially be predicted? Participants admitted o the ICU will wear a digital device to collect biometric data and will have serial plasma samples collected during ICU admission and patients will be also assessed for delirium daily by study staff.

Eligibility Criteria

Age Range: 65 years to No maximum

Inclusion Criteria: * Admitted to the intensive care unit * Able to consent or have a legally authorized representative consent on their behalf * English speaker * Expected ICU stay of 48 hours or more Exclusion Criteria: * Advanced dementia * End stage liver disease * Renal replacement therapy * Structural brain injury, including but not limited to traumatic brain injury, cerebrovascular accident and intracranial hemorrhage,

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Critical IllnessDelirium in the Intensive Care UnitSleep Quality

Locations

Scripps Green Hospital

La Jolla, California 92037

United States

Scripps Memorial La Jolla Hospital

San Diego, California 92117

United States