Dorsal Root Electrical Stimulation in Children With Cerebral Palsy
Start Date
7/16/2026
Completion Date
12/1/2029
Summary
The goal of this clinical trial is to evaluate whether dorsal root electrical stimulation could reduce spasticity in children with cerebral palsy (CP).
Detailed Description
The investigators will recruit participants with CP requiring selective dorsal rhizotomy (SDR) surgery. During SDR, spastic dorsal roots are routinely identified by electrically stimulating each root at low frequency (1 Hz) and measuring the resulting muscle response via electromyography - a procedure called "clinical test stimulation." Dorsal roots that produce an abnormally large and widespread compound muscle action potential (CMAP) are classified as spastic. In this study, the investigators will superimpose higher-frequency dorsal root stimulation (40-5000 Hz) on top of this standard clinical test stimulation and assess whether it suppresses the abnormal large CMAP.
Eligibility Criteria
Age Range: 3 years to 14 years
Interventions
Constant Current Stimulator
Cadwell Guardian System
Conditions
Locations
UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania 15224
United States