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NCT07718347NARecruiting

Post-market Cosmetic Evaluation of Ariessence™ Pure PDGF+ Following Ablative Laser

Lynch Regenerative Medicine

Start Date

4/16/2026

Completion Date

2/1/2027

Summary

ariessence is intended to be used as a viscous, leave-on solution designed for topical application to the face. It is intended to be used following non-medical cosmetic procedures, performed by licensed healthcare professionals to enhance comfort and maintain skin hydration. This study is designed to be a multi-center, post-market cosmetic evaluation of ariessence applied to the full face after an ablative laser procedure to evaluate improvements in procedure tolerability and improvements in the appearance of the skin, compared to an emollient control.

Detailed Description

To compare procedure tolerability of the treated facial area between ariessence and standard aftercare (Aquaphor). Tolerability, using subject tolerability assessments (subject diaries), investigator tolerability assessments, and standardized day-3/7/14 photographs, with site confirmation.

Eligibility Criteria

Age Range: 40 years to 70 years

Inclusion Criteria -:Adults 40-65 70 years * Glogau III-IV * Fitzpatrick II-IV. * Suitable for ablative laser * non-smoker ≥ 3 years * Willing to comply with post-procedure regimen * patient reported outcome documentation, and photo documentation. Exclusion Criteria: * Fitzpatrick I or \> IV, * recent facial procedures (\< 6 months) * active skin disease * pregnancy/lactation * implanted devices * history of keloids.

Interventions

OTHER

ariessence pure PDGF+™ is a sterile aqueous formulation containing Hyaluronic Acid and pure platelet-derived growth factor (PDGF).

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Conditions

Immediate Post-Treatment CareAging Mid-FaceAging

Locations

Laser & Skin Surgery Medical Group

Sacramento, California 95816

United States

The Practice of Brian S. Biesman, MD

Nashville, Tennessee 37203

United States