NCT07746167RecruitingAccepts Healthy Volunteers
Pupillary Dilation Reflex in Healthy Volunteers
Children's National Research Institute
Start Date
4/29/2026
Completion Date
6/1/2027
Summary
This a single site, observational study that will examine how the pupil responds to neurostimulation under different conditions in healthy adults. The objective is to measure pupillary dilation reflex (PRD) in response to increasing neurostimulation intensities using the AlgometRx device.
Eligibility Criteria
Age Range: 18 years to 60 years
Inclusion Criteria:
* Age 18-60 years.
* In good general health (self-reported).
* Able and willing to provide written informed consent.
Exclusion Criteria:
* Eye pathology that prevents accurate pupillometry.
* Pregnancy (Self-Report)
* Diagnosis of autoimmune disorders.
* Diagnosis of any neuropathic disorder
* Inability to complete questionnaires.
Interventions
OTHER
No intervention (observational study)
Conditions
Healthy Participants
Locations
Children's National Hospital
Washington D.C., District of Columbia 20010
United States