NCT07776704NARecruiting

Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients

Fox Chase Cancer Center

Start Date

8/21/2025

Completion Date

1/1/2029

Summary

This study compares two methods of prescribing parenteral nutrition (PN) in adults with cancer who are unable to meet nutritional needs by oral or enteral intake.

Detailed Description

This is a single-center, randomized, open-label pilot study enrolling 50 adult oncology patients requiring PN (parenteral nutrition). Participants are randomized to weight-based dosing or indirect calorimetry-guided dosing. Outcomes include feasibility, acceptability, changes in PN prescription, adverse events, quality of life, and survival.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Adults aged ≥18 years * Diagnosis of cancer * Requirement for PN ≥1 week * Ability to provide informed consent * English-speaking Exclusion Criteria: * Hospice enrollment * Mechanical ventilation * Chest tube or drain * Continuous renal replacement therapy * Supplemental oxygen

Interventions

DEVICE

Indirect Calorimeter

DIETARY_SUPPLEMENT

Weight-Based Parenteral Nutrition Dosing

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

MalnutitrionCancer

Locations

Fox Chase Cancer Center

Philadelphia, Pennsylvania 19111

United States