NCT07786467NARecruitingAccepts Healthy Volunteers
Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations
Lake Erie College of Osteopathic Medicine
Start Date
9/1/2026
Completion Date
10/1/2027
Summary
The investigators are studying if a specific osteopathic manipulative treatment protocol can improve the immune response (antibody titers) to seasonal influenza vaccination in vulnerable populations, including patients with advanced age and/or adiposity.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Willing to receive OMT
* Willing to receive influenza vaccine
* Older than 18 years of age
Exclusion Criteria:
* Younger than 18 years of age
* Pregnancy or lactation
* Unwilling to receive the influenza vaccine
* Unwilling to receive OMT
* Open wounds
* Bone fractures
* Moderate to severe osteoporosis
* Severe COPD
* Current/active infections
* Mononucleosis infection within past 6 months
* Liver cirrhosis
* Cancer or metastatic disease
* History of DVT, PE, or blood clotting disorder
* Individuals taking blood thinning medications, except aspirin
* Having a pacemaker or other thoracic medical devices
Interventions
OTHER
Osteopathic Manipulation
OTHER
Osteopathic manipulation
OTHER
Sham
Conditions
No Disease or Condition is Being Directly StudiedThe Focus of the Study in Healthy Volunteers
Locations
Plaza 38 Medical Offices
Erie, Pennsylvania 16509
United States