NCT07786818RecruitingAccepts Healthy Volunteers
Metatranscriptomic Markers of Colonic Neoplasia
Viome
Start Date
12/20/2025
Completion Date
1/30/2027
Summary
This study is a collaboration between Viome Life Sciences and Scripps Research Institute to develop and validate a noninvasive molecular diagnostic test for the detection of colorectal polyps. Approximately 1,000 participants undergoing colonoscopy will provide saliva and stool samples prior to their procedure. Molecular features identified in these samples will be evaluated in relation to colonoscopy findings to develop a predictive model for colorectal polyp detection. The resulting model will then be evaluated in an independent validation dataset to assess its performance for identifying individuals with colorectal polyps.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Male or female, aged 18 years or older
* Undergoing colonoscopy with bowel preparation
* Able to provide stool and saliva samples prior to colonoscopy
* No stoma present
* No known personal history of colorectal cancer
Exclusion Criteria:
* Individuals under 18 years of age
* Patients with a stoma
* Personal history of colorectal cancer
Interventions
OTHER
This is an observational study that has no interventions
Conditions
Colorectal Polyps
Locations
Viome Life Sciences
Bothell, Washington 98011
United States