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NCT07812545NARecruiting

Designing Effective Alcohol Health Warnings: An Experimental Study With Adults in the U.S.

University of Oklahoma

Start Date

7/27/2026

Completion Date

9/1/2026

Summary

Consuming alcohol is a dose-dependent and modifiable risk factor for breast cancer. Although alcohol consumption contributes to an estimated 16% of breast cancer cases, awareness of the link between alcohol and breast cancer risk remains low. Systematically developed and tested health warnings can support population-based approaches and intervention strategies to decrease alcohol consumption and breast cancer risk. For instance, the U.S. Food and Drug Administration can mandate specific warnings through statements (e.g., "WARNING: This product contains nicotine…") and color graphics depicting the negative health consequences of products that can harm public health, such as tobacco and alcohol. However, health warning statements and graphics should be assessed among intended audiences before implementation. Research has outlined principles for effective health warning statements. This project will test different health warning statements about the health effects of alcohol.

Detailed Description

Health warning statements should be assessed for effectiveness among target audiences before implementation as interventions. Research has outlined principles for effective health warning statements. Specifically, health warning statements are effective when they impact mediators of health behavior (e.g., message perceptions, emotional/affective reactions, and resistance to messages) as well as actual behavior. Guided by these assumptions, we will conduct an online randomized clinical trial (RCT) (N=2,000) with US female participants (ages 18 to 65 years) who report consuming alcohol in the past 30 days (i.e., people who currently drink) and young adult female non-drinkers (ages 18-29) to assess how both samples rate different alcohol health warning statements presented in different formats.

Eligibility Criteria

Age Range: 18 years to 65 years

Inclusion Criteria: * being between 18 and 65 years of age * assigned female at birth * self-report having consumed alcohol in the last 30 days for the current drinker groups * self-report not having consumed alcohol in the last 30 days for the nondrinker groups * live in the US and able to read, speak, and understand English

Interventions

BEHAVIORAL

Health warning statement evaluations (bottles)

BEHAVIORAL

Health warning statement evaluations (ads)

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Conditions

Risk PerceptionsDecision MakingAlcohol

Locations

University of Oklahoma Health Campus, Health Promotion Research Center

Oklahoma City, Oklahoma 73104

United States