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NCT07818889NARecruiting

Study to Refine the Effectiveness of New Generation Therapies for Suicide

Ohio State University

Start Date

4/29/2026

Completion Date

12/31/2029

Summary

The purpose of this research study is to improve the effectiveness of a well-established therapy for suicidal thoughts and behaviors called Brief Cognitive Behavioral Therapy (BCBT) for Suicide Prevention.

Detailed Description

Funded by The Jordan Elizabeth Harris Foundation, this study uses a Sequential Multiple Assignment Randomized Trial (SMART) design to evaluate how various sequences and doses of BCBT components differentially impact suicide risk. In this two-stage clinical trial, all participants will initially receive 4 sessions of BCBT and complete weekly assessments. They will also complete 4 weeks of ecological momentary assessment (EMA) and digital phenotyping procedures during the first month of treatment.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * 18 years of age or older; suicidal ideation (assessed with the SSI) and/or suicidal behavior within the past month (assessed with the SITBI-R), psychiatric hospitalization for elevated suicide risk within the past month, and/or SCS-R total score \>21; eligibility to understand and speak the English language; ability to complete the informed consent process Exclusion Criteria: * impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania) and/or a medical or psychiatric condition that precludes the ability to engage in outpatient therapy

Interventions

BEHAVIORAL

Brief Cognitive Behavioral Therapy

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Conditions

Suicide RiskSuicide AttemptTreatment Response

Locations

Department of Psychiatry and Behavioral Health

Columbus, Ohio 43210

United States