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NCT07824648NARecruiting

Thermoregulatory Physiology of Menopausal Hot Flashes

SRI International

Start Date

5/5/2026

Completion Date

9/15/2027

Summary

This study is evaluating the effects of cooling on menopausal hot flashes in midlife women. Precise targeted cooling is provided to areas of the skin when a hot flash occurs.

Eligibility Criteria

Age Range: 40 years to 65 years

Inclusion Criteria: * Female * Age range: 40 to 65 years and in menopausal transition or post-menopause; * At least 8 years of education to ensure adequate reading proficiency; * Primary language is English or Spanish. Exclusion Criteria: * History of medical or neurological illness or trauma that would affect the central nervous system (e.g., stroke, multiple sclerosis, epilepsy); * Current severe medical conditions (e.g. Diabetes, cancer, cardiovascular disease, renal or hepatic disease, thyroid disorders); * History of schizophrenia and/or bipolar disorder; * Dependence or abuse of illicit substances in the past year; * Current use of hormone therapy or other treatments for hot flash symptoms

Interventions

OTHER

Intervention C (Targeted skin cooling)

OTHER

Intervention B (Ambient cooling)

OTHER

Intervention A (Room temperature)

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Conditions

Menopause Hot Flashes

Locations

SRI International

Menlo Park, California 94025-3453

United States