NCT07824648NARecruiting
Thermoregulatory Physiology of Menopausal Hot Flashes
SRI International
Start Date
5/5/2026
Completion Date
9/15/2027
Summary
This study is evaluating the effects of cooling on menopausal hot flashes in midlife women. Precise targeted cooling is provided to areas of the skin when a hot flash occurs.
Eligibility Criteria
Age Range: 40 years to 65 years
Inclusion Criteria:
* Female
* Age range: 40 to 65 years and in menopausal transition or post-menopause;
* At least 8 years of education to ensure adequate reading proficiency;
* Primary language is English or Spanish.
Exclusion Criteria:
* History of medical or neurological illness or trauma that would affect the central nervous system (e.g., stroke, multiple sclerosis, epilepsy);
* Current severe medical conditions (e.g. Diabetes, cancer, cardiovascular disease, renal or hepatic disease, thyroid disorders);
* History of schizophrenia and/or bipolar disorder;
* Dependence or abuse of illicit substances in the past year;
* Current use of hormone therapy or other treatments for hot flash symptoms
Interventions
OTHER
Intervention C (Targeted skin cooling)
OTHER
Intervention B (Ambient cooling)
OTHER
Intervention A (Room temperature)
Conditions
Menopause Hot Flashes
Locations
SRI International
Menlo Park, California 94025-3453
United States