Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release
Start Date
9/25/2026
Completion Date
11/1/2027
Summary
This study is comparing two ways to manage pain after a major hernia repair surgery called "transversus abdominis release." One method uses an epidural, a small tube placed in the back that delivers pain medicine directly around the spine. The other method avoids the epidural and instead uses a combination of non-opioid pain medicines, along with an injection of numbing medicine into the abdominal wall during surgery. Patients who still have pain that is hard to control with either method will be given rescue pain medicine through an intravenous (IV) pump. Researchers want to learn which method controls pain better and results in patients using fewer opioid pain medicines after surgery. Participants will be randomly assigned (like a coin flip) to one of the two pain control methods. Pain levels and medication use will be tracked during the hospital stay, and participants will be contacted 30 days after surgery to check on recovery and any side effects.
Eligibility Criteria
Age Range: 18 years to 80 years
Interventions
Bupivicaine
Fentanyl
Thoracic epidural analgesia
Hydromorphone
Acetaminophen
Ketorolac
magnesium sulfate
Tramadol
Gabapentin
Cyclobenzaprine
transversus abdominis plane block
Conditions
Locations
Northwestern Memorial Hospital
Chicago, Illinois 60611
United States