Back to Trials
NCT00949819Recruiting

Active Surveillance for Cancer of the Prostate (ASCaP)

Jonsson Comprehensive Cancer Center

Start Date

7/4/2009

Completion Date

12/1/2028

Summary

Active Surveillance (A.S.) of prostate cancer (CaP) is the systematic monitoring of men with low-risk, localized lesions, with curative treatment of those whose tumors show substantial progression. A.S. is different from Watchful Waiting (W.W.), which is the palliative treatment of men with progressive prostate cancer.

Detailed Description

This protocol is not designed as a formal clinical trial, but rather an observational protocol; no treatments and no randomization are included. Longitudinally, specimens and clinical data will be collected to provide information on the following: * Imaging studies of the prostate * Rates of curative intervention * Measures of tumor recurrence/progression * Disease specific survival * Overall survival * Clinical data to track Quality of Life

Eligibility Criteria

Age Range: 30 years to 85 years

Inclusion Criteria: 1. Histologically confirmed adenocarcinoma of the prostate. 2. Clinically localized prostate cancer: T1-2, NX or N0, MX or M0. 3. No previous treatment for prostate cancer (including hormonal therapy, radiation therapy, surgery, or chemotherapy). 4. Patient has elected Active Surveillance as preferred management plan for prostate cancer. 5. Patient consent has been obtained according to local Institutional Review Board . 6. Patient is accessible and compliant for follow-up. Exclusion Criteria: 1. Unwillingness or inability to undergo serial prostate biopsy. 2. Overall life expectancy less than 2 years 3. Advanced prostate cancer

Interventions

OTHER

Active surveillance

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Prostate Cancer

Locations

University of California Los Angeles

Los Angeles, California 90095

United States