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NCT01258231Recruiting

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Brigham and Women's Hospital

Start Date

8/1/2000

Completion Date

8/1/2030

Summary

This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.

Detailed Description

This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. In addition, we also examine blood and urine biomarkers (proteins).

Eligibility Criteria

Age Range: 20 years to 90 years

Inclusion Criteria: * Undergoing heart surgery * Willing to provide consent Exclusion Criteria: * Enrolled in a concurrent drug or device trial that precludes concurrent enrollment

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Conditions

Heart; Dysfunction Postoperative, Cardiac SurgeryGenetic Predisposition to DiseaseAtrial FibrillationMyocardial InfarctionHeart Failure

Locations

Brigham and Women's Hospital

Boston, Massachusetts 02115

United States

UT Southwestern Medical Center

Dallas, Texas 75390-9068

United States

Department Texas Heart Institute at St. Luke's Episcopal Hospital

Houston, Texas 77225

United States