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NCT02708134Recruiting

Quality of Pediatric Resuscitation in a Multicenter Collaborative

Children's Hospital of Philadelphia

Start Date

5/2/2016

Completion Date

1/1/2030

Summary

This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.

Detailed Description

Cardiac arrests in children are a major public health problem. Thousands of children each year in the USA are treated with cardiopulmonary resuscitation (CPR) and managed after their cardiac arrest. Neurological outcomes following these in-hospital CPR events are often abnormal. As children with neurological deficits following CPR are a major burden for families and society, improving neurological outcomes through superior chest compression delivery during CPR and optimal care and management after cardiac arrest is an important clinical goal. Therefore, the objective of this investigation is to obtain evidentiary support to associate the relationship of quantitative CPR quality data (depth, rate, chest compressions (CC) fraction, compression release) during CPR, post-cardiac arrest care (PCAC) and patient survival in those children who suffer an arrest within the study (RES-Q) Network.

Eligibility Criteria

Age Range: No minimum to 18 years

Inclusion Criteria: * Patient received chest compressions for at least 1 minute * Patient between gestational age ≥37 weeks and 18 years of age Exclusion Criteria: * Patient on veno-arterial extracorporeal membrane oxygenation (ECMO) therapy at beginning of CPR event

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Conditions

Cardiac ArrestCardiopulmonary Arrest

Locations

Kaiser Permanente

Los Angeles, California 90027

United States

Cedars-Sinai Medical Center

Los Angeles, California 90048

United States

Valley Children's Hospital

Madera, California 93636

United States

Chldren's Hospital of Orange County

Orange, California 92868

United States

Stanford University

Palo Alto, California 94304

United States

Rady Children's Hospital

San Diego, California 92123

United States

Children's Colorado

Aurora, Colorado 80045

United States

Nemours Children's Hospital

Wilmington, Delaware 19803

United States

All Children's Hospital

St. Petersburg, Florida 33701

United States

Children's Healthcare of Atlanta (CHOA)

Atlanta, Georgia 30322

United States

Lurie Children's (Children's Hospital of Chicago)

Chicago, Illinois 60611

United States

University of Chicago, Comer Children's Hospital

Chicago, Illinois 60637

United States

Riley Hospital for Children

Indianapolis, Indiana 46202

United States

University of Iowa Stead Family Children's Hospital

Iowa City, Iowa 52242

United States

Kentucky Children's Hospital

Lexington, Kentucky 40536

United States

The Johns Hopkins Hospital

Baltimore, Maryland 21287

United States

Massachusetts General Hospital

Boston, Massachusetts 02114

United States

Boston Children's

Boston, Massachusetts 02115

United States

St. Louis Children's Hospital

St Louis, Missouri 63110

United States

Nebraska Medical Center

Omaha, Nebraska

United States

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire 03756

United States

Albany Medical Center

Albany, New York 12208

United States

Mount Sinai Kravis Children's Hospital

New York, New York 10029

United States

Morgan Stanley Children's Hospital

New York, New York 10032

United States

Cohen Children's Medical Center

Queens, New York 11040

United States

Stony Brook University Hospital

Stony Brook, New York 11794

United States

Upstate Golisano Children's Hospital

Syracuse, New York 13210

United States

University of North Carolina

Chapel Hill, North Carolina 27514

United States

Akron Children's

Akron, Ohio 44308

United States

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio 45229

United States

Nationwide Children's Hospital

Columbus, Ohio 43205

United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania 19104

United States

Medical University of South Carolina

Charleston, South Carolina

United States

Dell Children's Medical Center

Austin, Texas 78723

United States

Medical City Children's Hospital

Dallas, Texas 75230

United States

University of Texas Southwestern

Dallas, Texas 75390

United States

The Children's Hospital of San Antonio

San Antonio, Texas 78207

United States

Children's Hospital of Richmond at VCU

Richmond, Virginia 23219

United States

Seattle Children's Hospital

Seattle, Washington 98105

United States

Medical College of Wisconsin

Milwaukee, Wisconsin 53226

United States

The Children's Hospital at Westmead

Westmead, New South Wales 2145

Australia

Perth Children's Hospital

Nedlands, 6009

Australia

Queensland Children's Hospital

South Brisbane, 4101

Australia

Sabara Hospital Infantil

São Paulo, 01227-200

Brazil

Stollery Children's Hospital

Edmonton, Alberta T6G 2B7

Canada

BC Children's

Vancouver, British Columbia V6H 3N1

Canada

Alberta Children's

Calgary, AB T3B

Canada

Instituto Roosevelt

Bogotá,

Colombia

IRCCS Ospedale Pediatrico Bambino Gesù

Roma, 486686

Italy

Aichi Children's Health and Medical Center

Aichi, 474-8710

Japan

Kobe Children's Hospital (Hyogo Prefectural)

Kobe, 650-0047

Japan

Tokyo Metropolitan Children's Medical Center

Tokyo, 183-8561

Japan

Erasmus MC - Sophia Children's

Rotterdam, 3015

Netherlands

Starship Children's Hospital

Auckland, 1023

New Zealand

National University Hospital

Singapore, 119074

Singapore

KK Women's & Children's Hospital

Singapore, 229899

Singapore

Seoul National University Bundang Hospital

Seongnam, 13620

South Korea

Gregorio Marañón General University Hospital

Madrid, 46 28007

Spain

National Taiwan University Hospital

Taipei, 100229

Taiwan

King Chulalongkorn University

Bangkok, 10330

Thailand

Great Ormond Street Hospital

London, WC1N 3JH

United Kingdom