Back to Trials
NCT03492424Recruiting

Ablative Therapy in the Management of Prostate Cancer

Weill Medical College of Cornell University

Start Date

1/2/2018

Completion Date

9/2/2039

Summary

The purpose of this study is collect observational data regarding patterns of care and outcomes of focal therapies for prostate cancer, including but not limited to: high-intensity focused ultrasound (HIFU), cryotherapy, focal laser ablation, irreversible electroporation, photodynamic therapy, and brachytherapy.

Detailed Description

Through the use of a pro- and retrospective registry, the investigators will collect information on patient characteristics including age, co-morbidities, imaging and biopsy information, and prior treatments. Information on treatment details will also be captured, including treatment time, anesthesia delivered, and length of stay, when applicable. Oncologic outcomes including PSA, post-treatment biopsy and imaging data, need for re-treatment, and survival outcomes will also be captured. Safety outcomes will be captured using the Clavien-Dindo classification scale, and additional specific GU complications will be recorded, which include urinary retention, urethral stricture, recto-urethral fistula, osteomyelitis, and urinary tract infection. Finally, the investigators will capture functional outcomes using health related quality of life questionnaires including the EPIC questionnaire, IIEF-5, MSHQ-EjD, and IPSS.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * \>18 years of age * Undergoing focal therapy for primary or salvage treatment of prostate cancer, or * Have received prior focal therapy Exclusion Criteria: * Clinically-evident metastatic disease * Unable to fill out an English-language questionnaire

Interventions

DEVICE

cryotherapy

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Prostate Cancer

Locations

Weill Cornell Medicine

New York, New York 10065

United States