NCT03747146NARecruitingAccepts Healthy Volunteers
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
Hospital for Special Surgery, New York
Start Date
11/16/2018
Completion Date
12/1/2026
Summary
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).
Detailed Description
Patients will be randomized to one of two groups: one group will receive a PAI, IPACK and single-shot adductor canal block; one group will receive PAI, IPACK and continuous adductor canal block catheter.
Eligibility Criteria
Age Range: 18 years to 65 years
Inclusion Criteria:
* Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
* Planned use of regional anesthesia
* Ability to follow study protocol
* English speaking (secondary outcomes include questionnaires validated in English only)
* Lives within one hour of the hospital
* Has a smart phone
Exclusion Criteria:
* Hepatic or renal insufficiency
* Younger than 18 years old or older than 65 years ol
* Patients undergoing general anesthesia
* Allergy or intolerance to one of the study medications
* BMI \>40
* Diabetes
* American Society of Anesthesiologists (ASA) status III or IV
* Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
* Patients with chronic pain (from a referral to chronic pain service) or a pain catastrophizing scale (PCS \>30)
* Patients with severe valgus deformity or flexion contracture
* Patients unable to follow home catheter instructions and unwilling to go home with an infusing catheter
* Patients who have no home caregivers in the event that a catheter is to be sent home with the patient
* Patients with planned stay at rehab facility (to avoid medical device being tampered with at the rehab facility)
* Non-English speakers (secondary outcomes include questionnaires validated in English only)
Interventions
DEVICE
Continuous Adductor Canal Catheter (ACC)
DEVICE
Adductor Canal block with sham catheter
Conditions
Anesthesia
Locations
Hospital for Special Surgery
New York, New York 10023
United States