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NCT03947697NARecruitingAccepts Healthy Volunteers

Improving Glycemic Control With Electrical Stimulation

University of Texas, El Paso

Start Date

8/9/2022

Completion Date

4/30/2027

Summary

Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55/15/30% CHO/PRO/FAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an 8-week electrical stimulation intervention (30min/day, 3x/week) and randomized into placebo/control, NMES, resistance training combined with NMES (RT +NMES), or resistance training (RT) group (n=15 per group), followed by collection of post-intervention data. The control group will receive electrical stimulation up to sensory level, the NMES group will receive stimulation up to tolerable intensity to induce visible muscle contraction, the RT+ NMES will receive stimulation up to tolerable intensity during resistance training, and the RT group will only receive exercise training. Pre-and post-intervention data includes measurements for body composition, resting metabolic rate, VO2max, insulin sensitivity, and comprehensive blood work.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Overweight/Obese (BMI ≥25) * Sedentary Lifestyle: Physical Activity Level\<1.4 * Less than 150min/week of structured Exercise Exclusion Criteria: * Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications * Excessive alcohol, drug abuse, smoking * Pregnant Women * Unwilling to adhere to the study Intervention

Interventions

DEVICE

Neuromuscular Electrical Stimulation (Sensory)

DEVICE

Neuromuscular Electrical Stimulation

OTHER

Resistance Training

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Conditions

ObesityOverweightInsulin Resistance

Locations

University of Texas at El Paso

El Paso, Texas 79968

United States