NCT03948893NARecruitingAccepts Healthy Volunteers
Smoking Cessation Behavioral Treatment Study
University of Missouri-Columbia
Start Date
12/19/2019
Completion Date
3/31/2025
Summary
The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Age 18 and up
* English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks
* Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks
* Current nicotine dependent smoker with a minimum smoking history of 2 years
* Interest in quitting smoking
Exclusion Criteria:
* Use of psychotropic (e.g. antiepileptic) medications in the past month
* Positive urine drug screen
* Presence of an untreated medical illness
* Current or past psychosis
* History of major neurological illness or head injury resulting in loss of consciousness
* And contraindication to MRI, including claustrophobia
* Among females, positive urine pregnancy test
* Inability or unwillingness of subject to give informed consent
Interventions
BEHAVIORAL
Mindfulness-Oriented Recovery Enhancement (MORE)
BEHAVIORAL
Cognitive Behavioral Therapy (CBT)
Conditions
Tobacco Use Disorder
Locations
University of Missouri - Columbia
Columbia, Missouri 65211
United States
Medical University of South Carolina
Charleston, South Carolina 29425
United States