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NCT03948893NARecruitingAccepts Healthy Volunteers

Smoking Cessation Behavioral Treatment Study

University of Missouri-Columbia

Start Date

12/19/2019

Completion Date

3/31/2025

Summary

The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Age 18 and up * English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks * Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks * Current nicotine dependent smoker with a minimum smoking history of 2 years * Interest in quitting smoking Exclusion Criteria: * Use of psychotropic (e.g. antiepileptic) medications in the past month * Positive urine drug screen * Presence of an untreated medical illness * Current or past psychosis * History of major neurological illness or head injury resulting in loss of consciousness * And contraindication to MRI, including claustrophobia * Among females, positive urine pregnancy test * Inability or unwillingness of subject to give informed consent

Interventions

BEHAVIORAL

Mindfulness-Oriented Recovery Enhancement (MORE)

BEHAVIORAL

Cognitive Behavioral Therapy (CBT)

Interested in This Trial?

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Conditions

Tobacco Use Disorder

Locations

University of Missouri - Columbia

Columbia, Missouri 65211

United States

Medical University of South Carolina

Charleston, South Carolina 29425

United States