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NCT04275557Recruiting

Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

H. Lee Moffitt Cancer Center and Research Institute

Start Date

2/18/2020

Completion Date

6/1/2027

Summary

The Florida Pancreas Collaborative wants to partner with individuals who are known to have, or are suspected to have a pancreatic lesion, tumor, cyst, mass, cancer, or pancreatitis and are undergoing diagnosis and treatment at a participating institution. The goals of this project are to build a large database of information obtained from blood, tissue, medical images, surveys and information from routine care to develop noninvasive diagnostic approaches that could be used as decision-making tools to effectively personalize clinical care.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Individuals who present to the GI clinic, surgery, or endoscopy at Moffitt, Florida Research Institute (FRI), or UM with a clinical suspicion for (or diagnosis of) a pancreatic lesion, cyst, mass, cancer, or pancreatitis based on symptoms, imaging, or blood-work and has not had any treatment involving their pancreas. * Able to understand and voluntarily sign the informed consent. * Willing to complete study questionnaire(s) and donate medical images and/or biological specimens (including blood, cystic fluid, and/or tissue) obtained at the time of standard of care procedures (biopsy, surgery, and venipuncture) after signing the informed consent document Exclusion Criteria: * No suspicion or diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis. * Has a diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis and has already undergone treatment involving the pancreas (which may involve surgery, chemo- or immuno-therapy, and/or radiation). * Unable to provide informed consent. * Unwilling to complete study questionnaire(s) and/or donate biological specimens or images.

Interventions

OTHER

Blood Sample collection

OTHER

Tissue sample collection

OTHER

Data collection

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Conditions

Pancreatic CancerPancreatic Cyst

Locations

Florida Research Institute (FRI)

Lakewood Rch, Florida 34211

United States

Sylvester Comprehensive Cancer Center & Jackson Memorial Hospital

Miami, Florida 33136

United States

Moffitt Cancer Center

Tampa, Florida 33612

United States