Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
Start Date
11/1/2021
Completion Date
3/31/2029
Summary
This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major adverse kidney events in in patients with congestive heart failure undergoing cardiac catheterization and/or percutaneous coronary intervention.
Detailed Description
The RICH Trial is a prospective, multicenter, randomized clinical trial to determine the effect of remote ischemic preconditioning on contrast associated acute kidney injury, and to characterize the effect of remote ischemic preconditioning on brain natriuretic peptide, functional capacity at one month, and major adverse kidney events (persistent renal dysfunction, renal replacement therapy, and death) at three months in patients with congestive heart failure with reduced left ventricular ejection fraction undergoing coronary angiography and/or percutaneous coronary intervention.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Remote ischemic preconditioning
Sham remote ischemic conditioning
Conditions
Locations
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
Pittsburgh, Pennsylvania 15240
United States
VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX
Dallas, Texas 75216-7167
United States
Hunter Holmes McGuire VA Medical Center, Richmond, VA
Richmond, Virginia 23249-0001
United States