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NCT05181826Recruiting

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

Helio Genomics

Start Date

5/21/2019

Completion Date

1/1/2028

Summary

To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for the detection of various types of cancer, ii) identifying benign conditions that may induce false positive or false negative results, and iii) defining the effects of potential interfering substances, such as chemotherapy drugs.

Detailed Description

Whole blood, plasma, and/or serum specimens will be collected from patients with active cancer, patients in cancer remission, patients diagnosed with benign disease, and healthy volunteers. These blood samples will be used to perform various studies to determine the utility of select DNA methylation markers for cancer diagnostic or prognostic indications.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: 2.1.1 Age 18 years or older. 2.1.2 A diagnosis of cancer, cancer remission, benign disease (benign tumor, diabetes, liver cirrhosis, chronic hepatitis B or hepatitis C virus infection, Chronic obstructive pulmonary disease, etc.) or apparently healthy volunteers. . Exclusion Criteria: 2.2.1 Patients that are unwilling or unable to sign the Informed Consent Form will be excluded. 2.2.2 Approximately 50 mL of blood will be drawn from participants within an 8-week period under this protocol. Patients that have already given 50 mL of blood within this time frame will be excluded.

Interventions

DIAGNOSTIC_TEST

Multi-analyte Blood Test

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Conditions

CancerLiver CirrhosisChronic HepatitisHepatitis BHepatitis CDiabetesCOPD

Locations

Torrance Memorial Physician Network - Cancer Care

Redondo Beach, California 90277

United States

Allina Health, Virginia Piper Cancer Institute

Coon Rapids, Minnesota 55433

United States

Virginia Piper Cancer Institute Mercy Hospital-Unity Campus

Fridley, Minnesota 55432

United States

VPCI Oncology Research

Minneapolis, Minnesota 55407

United States

Methodist LeBonheur Healthcare

Memphis, Tennessee 38104

United States

Liver Center of Texas

Dallas, Texas 75234

United States

Methodist Hospital

Richardson, Texas 75082

United States