NCT05193968NARecruitingAccepts Healthy Volunteers
Hot Flashes and Neurovascular Function in Women
Mayo Clinic
Start Date
2/24/2022
Completion Date
12/1/2026
Summary
Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship. As such, these studies are designed to provide a major step forward in understanding the link between hot flashes and neurovascular dysfunction and, by extension, cardiovascular disease in women.
Eligibility Criteria
Age Range: 40 years to 60 years
Inclusion Criteria:
* Non-smokers.
* Non-obese.
* Have at least one ovary.
* Free from cardiovascular disease.
* Not taking medications influencing cardiovascular function.
Exclusion Criteria:
\- None.
Interventions
OTHER
Sympathoexcitatory stressors
DRUG
Sodium Nitroprusside
DRUG
Acetylcholine
DRUG
Terbutaline
DRUG
Norepinephrine
Conditions
Hot FlashesMenopauseVasomotor System; Labile
Locations
Mayo Clinic in Rochester
Rochester, Minnesota 55905
United States