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NCT05220202NARecruiting

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

VA Office of Research and Development

Start Date

9/20/2023

Completion Date

12/1/2026

Summary

The proposed study seeks to evaluate effectiveness, implementation processes, and cost of MOTIVATE among older Veterans with chronic musculoskeletal (MSK) pain and comorbid depressive symptoms.

Detailed Description

Investigators will conduct a randomized controlled trial (RCT) at two large VA facilities, to establish the effectiveness and scalability of MOTIVATE, a remotely delivered behavioral intervention for older Veterans with comorbid musculoskeletal (MSK) pain and depressive symptoms. The central hypothesis is that MOTIVATE will improve important patient-centered outcomes among older Veterans with co-occurring MSK pain and depressive symptoms.

Eligibility Criteria

Age Range: 60 years to 99 years

Inclusion Criteria: * Aged 60 and older * English- speaking * Self-reported MSK pain (include cLBP +/- radiating symptoms, OA, fibromyalgia) on most days for the past 3 months that interferes with daily activities * Pain intensity that is 4+/10 on the numerical pain rating scale * Pain interference threshold 5+ on PEG-3 * Depressive symptoms, 10+ on PHQ-9 * Capable of participating in home-based activity * Interested in participating in a non-pharmacologic program Exclusion Criteria: * Aged 59 or less * No telephone * Not English speaking * Unwilling to be randomized to either study arm * Not interested in participating in a non-pharmacologic program * Self-reported uncorrected hearing and visual impairments precluding ability to participate in telephone sessions or read pedometer screen * Significant (moderate or severe) cognitive impairment (3+ errors) on six-item screening exam * Self-reported dependence on wheelchair, bed-bound, or severe balance impairment or severe OA\* (resulting in inability to participate in physical activity intervention) * Illness requiring hospitalization within the last 3 months that interferes with a home-based physical activity intervention (e.g., fall, gout attack, stroke, heart attack, heart failure, surgery for blocked arteries) * Suicidal intent (see suicide screening protocol), uncontrolled psychotic disorder or psychiatric hospitalization within 1 year, or enrolled in active substance use program (confirmed with scripted protocol over telephone)

Interventions

BEHAVIORAL

Behavioral Intervention Group (MOTIVATE)

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Conditions

Chronic Back PainDepressionAgingMusculoskeletal Pain

Locations

VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX

Dallas, Texas 75216-7167

United States

Michael E. DeBakey VA Medical Center, Houston, TX

Houston, Texas 77030-4211

United States