Computational Neuroscience of Language Processing in the Human Brain
Start Date
4/2/2021
Completion Date
3/31/2027
Summary
Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light on the construction and understanding of speech.
Detailed Description
The neural architecture of language is the foundation for the highest form of human interaction. Prior work has identified a network of frontal and temporal brain areas that selectively support language processing, but the precise computations that underlie our ability to extract meaning from sequences of words have remained unknown. The standard approaches in human cognitive neuroscience lack the spatial and temporal resolution necessary for precise comparisons to computational models. To bridge this gap in knowledge, neural responses to language stimuli will be collected from epileptic patients undergoing intracranial monitoring. Overall, these data will be used to identify cortical maps of different linguistic manipulations and to better understand properties of the human language network.
Eligibility Criteria
Age Range: 18 years to 85 years
Interventions
Behavioral tasks during intracranial monitoring
Conditions
Locations
Massachusetts General Hospital
Boston, Massachusetts 02114
United States