TERPS Trial for de Novo Oligometastic Prostate Cancer
Start Date
10/18/2022
Completion Date
7/31/2029
Summary
This research is being done to see if we can improve the outcome of prostate cancer patients who present with metastatic lesions at initial diagnosis.
Detailed Description
This study will compare the effects, good and/or bad, of using the standard of care treatment (systemic therapy + primary prostate radiation) compared to standard of care treatment plus stereotactic ablative radiation therapy (SABR) to metastatic lesions for prostate patients. The researchers are also trying to learn if the addition of SABR will affect recurrence rates. Presence of circulating tumor cells, gut bacteria, and quality of life will be assessed for both groups.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Prostate radiation (XRT)
Systemic Therapy
Stereotactic ablative radiation therapy (SABR)
Conditions
Locations
UC San Diego Moores Cancer Center
La Jolla, California 92093
United States
KU Medical Center- Cancer Center
Kansas City, Kansas 66160
United States
Maryland Proton Treatment Center
Baltimore, Maryland 21201
United States
UMMC
Baltimore, Maryland 21201
United States
Upper Chesapeake Health
Bel Air, Maryland 21014
United States
Central Maryland Radiation Oncology
Columbia, Maryland 21044
United States
Baltimore Washington Medical Center
Glen Burnie, Maryland 21061
United States
Sidney Kimmel Cancer Center at Jefferson Health
Philadelphia, Pennsylvania 19107
United States
UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania 15232
United States
Bon Secours Cancer Institute at St. Francis
Midlothian, Virginia 23114
United States