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NCT05248581Recruiting

Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases

University of Rochester

Start Date

8/16/2019

Completion Date

8/1/2027

Summary

The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.

Detailed Description

The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation. Our primary outcome of interest was the OS and recurrence-free survival (RFS) of patients who underwent LDLT at our center.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Age ≥ 18 * Non-amenable to curative hepatic resection as defined by FLR \<30% * Histologically confirmed adenocarcinoma of the colon or rectum * Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program Exclusion Criteria: * Not a candidate of the LDLT liver transplant protocol for treatment of colorectal liver metastasis. * Unwilling to consent

Interventions

PROCEDURE

Liver transplantation

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Conditions

Colorectal Cancer Metastatic

Locations

University of Rochester Medical Center

Rochester, New York 14642

United States