Laryngeal Cryotherapy for Refractory Neurogenic Cough
Start Date
12/26/2022
Completion Date
2/1/2027
Summary
This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure
Detailed Description
This study aims to test a new type of treatment for patients suffering from chronic cough, also known as upper airway cough syndrome. The new treatment involves the use of laryngeal cryotherapy which is the therapeutic freezing of tissue in the throat to numb the overactive sensory nerves in the throat which is believed to reduce cough symptoms. Patients will first undergo a flexible scope of the throat (laryngoscopy) to test for hypersensitive areas in the throat, then undergo the cryotherapy procedure in the office. After that, patients will be followed up in the clinic with the usual standard of care visits and undergo validated cough surveys to track their cough symptoms after the procedure. Possible side effects to this procedure are listed in detail below, and include temporary throat pain and coughing.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Laryngeal cryotherapy
Cryoprobe
Conditions
Locations
UT Southwestern Medical Center
Dallas, Texas 75235
United States