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NCT05733091Recruiting

Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors

M.D. Anderson Cancer Center

Start Date

12/20/2018

Completion Date

12/31/2029

Summary

To learn about the symptoms and changes our patients experience while receiving treatment for sinonasal or nasopharyngeal cancer

Detailed Description

Objectives: * To estimate the prevalence and severity of adverse and functional outcomes in survivors of benign and malignant paranasal sinus, nasopharynx and skull base tumors. * To estimate the prevalence of health promotion behaviors during skull base tumor survivorship * To identify possible mediators or predictors of survivorship outcomes and health behaviors in survivors of skull base tumors. * To develop a database of demographic, clinicopathologic, recurrence, survival, functional and patient reported outcomes (PROS) for patients with benign and malignant paranasal sinus, nasopharyngeal and skull base tumors. * To assess the utility and limitations of PROs in evaluating functional impairments and symptom burden in skull base patients.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion criteria: 1. Previously untreated patients with or suspected to have sinonasal malignancy or nasopharyngeal malignancy diagnosis based on either outside pathology report or MD Anderson pathology report. 2. Age ≥ 18 years 3. Plan to obtain the majority of treatment at MDACC including surgery and radiotherapy 4. Ability to understand and willingness to sign written informed consent Exclusion criteria: 1. History of the previous solid or liquid malignancies, apart from skin cancers treated with local therapy. 2. Existing neurocognitive impairment that is not the result of sinonasal and nasopharyngeal cancers or is treatment. 3. Previous treatment for sinonasal or nasopharyngeal carcinomas, apart from biopsy.

Interventions

BEHAVIORAL

Standard of Care

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Conditions

Tumors

Locations

M D Anderson Cancer Center

Houston, Texas 77030

United States