NCT05766384Recruiting
Hyperpolarized 129Xe MRI Lung Health Cohort
University of Kansas Medical Center
Start Date
11/30/2023
Completion Date
3/31/2027
Summary
A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.
Eligibility Criteria
Age Range: 25 years to 35 years
Inclusion Criteria:
* Is enrolled in the American Lung Association Lung Health Cohort Study.
* Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date.
Exclusion Criteria:
* Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, \> 140 cm shoulder circumference, dependent on weight distribution).
* Is pregnant or breastfeeding
* Oxygen saturation (SpO2) \<88% on room air or with supplemental oxygen.
Interventions
DRUG
Hyperpolarized Xe129
Conditions
Healthy
Locations
University of Illinois-Chicago
Chicago, Illinois 60607
United States
University of Iowa
Iowa City, Iowa 52242
United States
University of Kansas Medical Center
Kansas City, Kansas 66160
United States
Duke University
Durham, North Carolina 27708
United States
Baylor College of Medicine
Houston, Texas 77030
United States
MD Anderson Cancer Center
Houston, Texas 77030
United States