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NCT06283472NARecruiting

Enhancing Prospective Thinking in Early Recovery (BEAM)

Indiana University

Start Date

6/17/2024

Completion Date

11/30/2027

Summary

The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question\[s\] this trial aims to answer are: * Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues? * Will high-intensity EFT cues effect greater treatment-seeking interest? * Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity) * Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS? * Will the novel behavioral SS decision-making task activate the nucleus accumbens? Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.

Eligibility Criteria

Age Range: 18 years to 60 years

Inclusion Criteria: * Individuals who meet current heavy drinking (≥2 heavy drinking days/month OR ≥7 drinks/week for biological females, and ≥14 drinks/week if biological male \[NIAAA definition\] and/or AUDIT scores ≥8) * English comprehension Exclusion Criteria: * Unstable medical disorders * Outside the age range of 18-60 * Smell/taste disorders * Unstable psychiatric conditions

Interventions

BEHAVIORAL

High-Intensity Cue

BEHAVIORAL

Low-Intensity Cue

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Conditions

Alcohol Use Disorder

Locations

Indiana University School of Medicine - Goodman Hall

Indianapolis, Indiana 46202

United States