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NCT06295588PHASE2Recruiting

Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer

University of Rochester

Start Date

7/26/2025

Completion Date

6/1/2027

Summary

To determine the feasibility of an 8-week fucoidan supplement intervention for patients with fatigue post-cancer treatment and assess changes in fatigue, frailty, and inflammation.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Survivors of cancer * Age 18 or older * Speak and understand English * Have completed surgery, radiation, and/or systemic intravenous anticancer therapy (e.g., chemotherapy, targeted therapy, immunotherapy) ≤10 years prior to enrollment. * Have a baseline level of fatigue, as determined by reporting a score of 4 or higher for the question, "In the last week, how bad was your worst fatigue on a scale from 0-10?" * Be willing to commit to the fucoidan supplement dosing and delivery method, to complete evaluation instruments, and to attend all study visits. * Completed Informed Consent Exclusion Criteria: * Current warfarin or other anti-coagulation medication use. * Current use of supplements that contain fucoidan * Any allergy to fucoidan * Be diagnosed with a major psychiatric illness requiring hospitalization within the last year. * Be diagnosed with dementia. * Be pregnant or nursing

Interventions

DRUG

Fucoidan extracted from F. Vesiculosus

DRUG

Fucoidan extracted from U. Pinnatifida

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Conditions

FatigueInflammation

Locations

University of Rochester Medical Center

Rochester, New York 14642

United States