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NCT06634381Recruiting

Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

Wake Forest University Health Sciences

Start Date

3/12/2025

Completion Date

6/1/2028

Summary

The purpose of this research study is to better understand how cancer-related fatigue affects patients and how it's discussed with providers. This information will be used to develop an educational resource (visual aid poster) that could help individuals and their providers talk about cancer-related fatigue and which may help individuals better manage this symptom.

Detailed Description

This is a mixed methods cross-sectional pilot study. The target population is adults ≥ 18 years of age who have been diagnosed with cancer, have completed anti-cancer treatment more than six months ago, have no current detectable evidence of cancer, and are experiencing cancer-related fatigue. Participation in this research will involve completion of a six-minute walk test, survey completion, two virtual video interviews, and potentially one additional virtual interview. The interviews will include two 45 minutes for survivors and one 30-minute interview for clinicians. An additional 30-minute interview will be conducted for each survivor and clinician group.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Ability to comply with study procedures for the duration of the study Survivors: * Written informed consent and HIPAA authorization for release of personal information * Ability to read/write, understand and converse in English without the need for an interpreter * Men and women aged ≥ 18 years at the time of consent * History of at least one visit for the purpose of monitoring long term care post curative treatment at LCH and/or the Charlotte or Winston-Salem campuses of AHWFBCCC * Completed curative treatment \> 6 months ago for any cancer type, with no detectable evidence of cancer * Self-reported tiredness, exhaustion, or weakness (i.e. fatigue) score of ≥ 4 on the Numerical Rating Scale * Adjuvant endocrine therapy to reduce the risk of cancer returning is acceptable (i.e. tamoxifen or aromatase inhibitors). Clinicians: \- Currently see oncology patients (any cancer type) for survivorship care at LCH and/or the Charlotte or Winston-Salem campuses of AHWFBCCC Exclusion Criteria: Survivors: * Continuing maintenance therapy or other cancer-related treatment (i.e. immunotherapy) * History of or current untreated Major Depressive Disorders or untreated severe depression * Hemoglobin \<11g/dL at last CBC SOC lab collection * History/diagnosis of dementia * Factors or conditions, for which participation may (1) not be in the best interest or (2) interfere with study assessment results (e.g. medical comorbidities, primary brain tumor/metastases) * No access to internet/Wi-Fi Clinicians: \- None

Interventions

BEHAVIORAL

CRF Visual Aid

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Conditions

CancerFatigue

Locations

Levine Childrens Hospital Pediatric Cancer and Blood Disorders

Charlotte, North Carolina 28203

United States

Levine Cancer Institute

Charlotte, North Carolina 28204

United States

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina 27157

United States