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NCT06399861NARecruiting

Humidity in Incubators for Tiny Infants

The University of Texas Health Science Center, Houston

Start Date

6/25/2024

Completion Date

7/1/2027

Summary

The objective of the study is to assess 2 different initial incubator humidification protocols for infants \<25 weeks' gestation admitted to the neonatal intensive care unit (NICU). The hypothesis is that a higher starting humidity decreases dehydration and results in no difference in survival or morbidity. Higher (90%) and lower (70%) starting humidity will be compared.

Eligibility Criteria

Age Range: No minimum to No maximum

Inclusion Criteria: * Inborn infant of \<25 weeks' gestation admitted to the NICU Exclusion Criteria: * Infants with known congenital skin conditions * Outborn infants * Infants with unknown gestational age prior to birth

Interventions

DEVICE

Incubator ambient relative humidity (RH) of 70%

DEVICE

Incubator ambient relative humidity (RH) of 90%

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Conditions

Extremely Premature Infant

Locations

Nationwide Children's Hospital - Grant Medical Center

Columbus, Ohio 43205

United States

Nationwide Children's Hospital - Ohio State University Wexner Medical Center

Columbus, Ohio 43210

United States

Children's Memorial Hermann Hospital

Houston, Texas 77030

United States

The Woman's Hospital of Texas

Houston, Texas 77054

United States

St. Luke's Baptist Hospital

San Antonio, Texas 78229

United States

North Central Baptist Hospital

San Antonio, Texas 78258

United States